Life Science

DSM Nutritional Products – Operating and Zone Concept for Fully Synchronized Production Processes

DSM Nutritional Products is the global market leader in innovative vitamin products and fine chemicals. As general contractor, IE Life Science carried out a GMP‑compliant conversion to establish fully synchronized production processes while operations continued uninterrupted.

Vitamin Boost for Productivity With GMP Compliance

Project

General planning of a production building in accordance with GMP guidelines and Planning and Execution as general contractor

Client

DSM Nutritional Products AG

Key Data

Planning & Execution
IE Life Science
Planning & Construction Period
10 months
Investment Volume
CHF 13 million

Working Together for Project Success

Services provided by IE Group

  • General planning and Planning and Execution as general contractor
  • Reorganization of personnel and material flows through a new zoning concept
  • Reduction of cleaning and changeover times through consistent use of CIP and WIP systems
  • Implementation of GMP compliance, SHE guidelines and hygiene requirements
  • Conversion during ongoing operation without affecting production
  • Process innovation through fully synchronized operating processes with minimal transport and handling times

Challenges & Solutions

Modification During Ongoing GMP Production Without Sacrificing Quality

Through careful construction process planning and consistent phasing of the works, IE Life Science ensured uninterrupted production throughout the entire project. Clearly defined separation concepts and time‑optimized construction steps ensured that GMP compliance was maintained at all times.

Fully Synchronized Production Processes Through an Intelligent Zone Concept

A well‑structured zoning concept with clearly defined hygiene areas and optimized routes formed the basis for synchronized production processes. CIP and WIP systems were integrated in a process‑oriented manner and have since ensured maximum operational efficiency and stable production performance.

The Project in Detail

DSM Nutritional Products is the global market leader in innovative vitamin products and fine chemicals for the food, pet food, pharmaceutical and cosmetics industries. With an annual output of approximately 40,000 tonnes, the Sisseln production site alone supplies more than half of global market demand.

To further improve both product quality and production volume, fully synchronized processes had to be implemented and existing industrial buildings comprehensively modernized. IE Life Science was commissioned as general planner and total contractor to carry out the GMP‑compliant conversion during ongoing operations.

The Challenge

The conversion project was subject to extremely high quality assurance and hygiene requirements. GMP compliance was therefore defined as a central requirement in the project specifications. At the same time, the conversion had to be carried out during ongoing production without any negative impact on manufacturing processes. In addition to the technical challenges, extensive coordination was required between authorities, company management, plant personnel and all project stakeholders – all of which was managed within the framework of comprehensive general planning.

Key Success Factors

rom the outset, IE Life Science contributed in‑depth expertise in modern industrial construction. Drawing on experience from pharmaceutical and food industry projects, a multi‑stage operating and zoning concept was developed based on the proven IE methodology. this concept optimized personnel and material flows while minimizing processing, cleaning and changeover times. CIP systems formed the technical basis for this approach, alongside strict adherence to GMP, SHE and hygiene requirements. In addition to the renovation of existing buildings, the construction of new cleanrooms, gowning areas and a warehouse formed an integral part of the holistic concept, resulting in a future‑proof and highly efficient production environment.

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